STUDY: AMPYRA (Dalfampridine) improves walking speed, walking endurance, and community participation in veterans with multiple sclerosis: a longitudinal cohort study

Conclusions: AMPYRA (Dalfampridine-ER) was associated with short-term improvements in walking speed and community participation, and sustained improvements in walking endurance and self-perceived impact of MS on walking for one year. Our study supports the utility of Ampyra in late MS. 
Objectives: The objective of this paper is to determine the clinical tolerability and effects of dalfampridine on walking and community participation.
Methods: All patients at the Portland VA Medical Center prescribed dalfampridine-ER over one year completed the Timed 25-Foot Walk, Multiple Sclerosis Walking Scale-12, Two-Minute Timed Walk, and Community Integration Questionnaire (CIQ) at baseline and follow-up clinic visits.

Multiple Sclerosis Journal. published 7 October 2013,10.1177/1352458513507356
Michelle H. Cameron, Oregon Health and Science University and Portland VA Medical Center, 3181 SW Sam Jackson Park Road, L226, Portland, OR 97219, USA. Email: cameromi@ohsu.edu